Euphrates means in the bible: A river important that flows through Armenia’s mountains and into the Persian Gulf. It was often called “the River” in Scripture. It marked the border of the promised land to Abraham’s seed Gen. 15/18; Deut. 1:7; Josh. 1:4; 1 Chr. 5:9; This boundary was established in David’s time 2 Sam. 8:3; 1 Chr. 18:3. Carchemish’s stronghold was constructed at the ford. This position was crucial in 2 Chr. military operations. 35:20; Jer. 46:2. The great city of Babylon was built on the Euphrates.
(in Bible Dictionary)