Bannayan syndrome means: The syndrome can also be associated with other features, such as down-slanting, eye-slitting, high-arched lips, joint hyperextensibility and pectus exavatum caved in chest. Strabismus, amblyopias seizures and mental retardation are some of the less common.
(in Medical Dictionary)
What else does Bannayan syndrome mean?
Bannayan Syndrome: This rare genetic condition is characterized by a macrocephaly, an enlarged head and multiple lipomas benign fat tumors. Hemangiomas benign vein tumors are also common. It does not cause cerebral ventricles to enlarge. Mild neurological impairment is possible, as well as postnatal growth retardation.
(in Medical Dictionary)
Named after George A. Bannayan, a Jerusalem-born American physician who first described the syndrome in 1971. It is possible that this was not the first report of the condition. Harris D. Riley, William R. Smith and William R. Smith reported the syndrome to be similar or very similar in 1960. This syndrome can also be called “macrocephaly”, multiple lipomas and hemangiomata. “.
(in Medical Dictionary)
The syndrome can be passed on to a child through an autosomal dominant trait. Affected parents have a 50% chance of passing the Bannayan gene on to their children. It is located on chromosome 10,q23.3. The mutation involves the PTEN homolog gene, which is a phosphatase-tensin homolog. Cowden disease is caused by a different PTEN mutation. This syndrome causes multiple hamartomas malformations that resemble tumors made up of mature tissue, particularly the breast, skin and mucous membranes.
(in Medical Dictionary)