25 or 6 to 4 means: It is a point where you are tired and don’t feel like going to sleep at night. Any activity, whether you’re writing or surfing the web, practicing a song or simply flicking through TV, is better than sleeping. It may seem like your only choice is to go to sleep when it’s 25, 6 to 4 or 25. You will then feel as though you’re missing out on some truly amazing thing that you could have seen or done if you were awake. The exact time at which this happens is “25 to 6 to 4”, approximately 25 to 26 minutes before 4AM. This name is after Chicago’s song. (in Slang Dictionary, added by Laila Decker)